It was observed that the most well studied membrane bound GST, microsomal glutathione transferase 1 (MGST1, EC number: 2.5.1.18) shared similarities with leukotriene C4 synthase (LTC4S, EC number: 4.4.1.20), catalyzing the conjugation reaction between leukotriene (LT) A4 and GSH
Glutathione in health and disease
58:10315-10322 (2010) Vu VH, Kim K
[DOI] [PubMed] [Google Scholar] 28.Masarone M., Rosato V., Dallio M., Gravina A.G., Aglitti A., Loguercio C., Federico A., Persico M
Key takeaways: The fetus cannot detoxify acetaminophen effectively and relies entirely on maternal metabolism
Irie et al.s study underscores the potential variability of GSHs effects across different NAFLD stages, possibly due to the greater severity of liver damage in NASH compared to NAFL